FEATURES

FAMILY

DESCRIPTION

Also known as CDX1_HUMAN, CDX1. Plays a role in transcriptional regulation (PubMed:24623306). Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the PRKD1 promoter in colorectal cancer (CRC) cells (PubMed:24623306). Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA (PubMed:28473536).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CDX1

Homeobox protein CDX-1

CDX1

Molecular Synopsis