FEATURES

FAMILY

DESCRIPTION

Also known as SAT1_MOUSE, Sat1, Sat. Enzyme which catalyzes the acetylation of polyamines (Probable). Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine > putrescine (By similarity). This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines (By similarity). Also involved in the regulation of polyamine transport out of cells (By similarity). Acts on 1, 3-diaminopropane, 1, 5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine (By similarity). Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

Sat1

Mutations

Mutation(s) distribution

Mutations table