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FEATURES

FAMILY

cytochrome P450 family

DESCRIPTION

Also known as ERYK_SACEN, eryK, CYP113A1. Responsible for the C-12 hydroxylation of the macrolactone ring of erythromycin. Thus, EryK catalyzes the hydroxylation of erythromycin D (ErD) at the C-12 position to produce erythromycin C (ErC). Erythromycin B (ErB) is not a substrate for this enzyme. Monomer.

Also known as ERYK_SACEN, eryK, CYP113A1. Responsible for the C-12 hydroxylation of the macrolactone ring of erythromycin. Thus, EryK catalyzes the hydroxylation of erythromycin D (ErD) at the C-12 ...

EXTERNAL LINKS

uniprot
enzyme classification

eryK

Erythromycin C-12 hydroxylase

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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