FEATURES

FAMILY

carnitine/choline acetyltransferase family

DESCRIPTION

Also known as CPT1A_HUMAN, CPT1A, CPT1. Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion (PubMed:9691089, PubMed:11350182, PubMed:14517221). Plays an important role in hepatic triglyceride metabolism (By similarity). Homohexamer and homotrimer (By similarity). Identified in a complex that contains at least CPT1A, ACSL1 and VDAC1 (By similarity). Also identified in complexes with ACSL1 and VDAC2 and VDAC3 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CPT1A

Carnitine O-palmitoyltransferase 1, liver isoform

CPT1A

Molecular Synopsis