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FEATURES

FAMILY

chloride channel (TC 2.A.49) family

DESCRIPTION

Also known as CLCN5_HUMAN, CLCN5, CLCK2. Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Important for normal acidification of the endosome lumen. May play an important role in renal tubular function. Interacts with NEDD4 and NEDD4L.

Also known as CLCN5_HUMAN, CLCN5, CLCK2. Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Important for normal acidification of the endo ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CLCN5

H(+)/Cl(-) exchange transporter 5

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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