FEATURES

FAMILY

DESCRIPTION

Also known as SPSY_HUMAN, SMS. Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM). Homodimer. Dimerization is mediated through the N-terminal domain and seems to be required for activity as deletion of the N-terminal domain causes complete loss of activity.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SMS

Spermine synthase

SMS

Molecular Synopsis