FEATURES

FAMILY

diphosphomevalonate decarboxylase family

DESCRIPTION

Also known as MVD1_HUMAN, MVD, MPD. Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MVD

Diphosphomevalonate decarboxylase

MVD

Molecular Synopsis