FEATURES

FAMILY

DESCRIPTION

Also known as KAD2_HUMAN, AK2, ADK2. Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. Monomer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

AK2

Adenylate kinase 2, mitochondrial

AK2

Molecular Synopsis