FEATURES

FAMILY

DESCRIPTION

Also known as CATK_MOUSE, Ctsk. Thiol protease involved in osteoclastic bone resorption. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation (By similarity). Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (PubMed:12782676).

EXTERNAL LINKS

uniprot
enzyme classification

Ctsk

Mutations

Mutation(s) distribution

Mutations table