FEATURES

FAMILY

DESCRIPTION

Also known as STMN2_MOUSE, Stmn2, Scg10, Scgn10, Stmb2. Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone. Interacts with ITM2C. Interacts with MAPK8. Interacts with KIFBP. Interacts (via the N-terminal region) with CIB1 (via C-terminal region); the interaction is direct, occurs in a calcium-dependent manner and attenuates the neurite outgrowth inhibition of STMN2.

Also known as STMN2_MOUSE, Stmn2, Scg10, Scgn10, Stmb2. Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in corti ...

EXTERNAL LINKS

uniprot
enzyme classification

Stmn2

Stathmin-2

Stmn2

Structural Ligandability

Domains Chains

Distribution