FEATURES

DESCRIPTION

Also known as BID_HUMAN, BID. Induces caspases and apoptosis (PubMed:14583606). Counters the protective effect of BCL2 (By similarity)., Induces caspase activation and apoptosis (PubMed:15661737). Allows the release of cytochrome c (By similarity)., Induces ICE-like proteases and apoptosis., Induces ICE-like proteases and apoptosis., Does not induce apoptosis., Induces ICE-like proteases and apoptosis. Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein BCL2 (By similarity). Interacts with PLEKHN1 (PubMed:29531808).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

BID

Mutations

Mutation(s) distribution

Mutations table