FEATURES

FAMILY

DESCRIPTION

Also known as PROF3_HUMAN, PFN3. Binds to actin and affects the structure of the cytoskeleton. Slightly reduces actin polymerization. Binds to poly-L-proline, phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4, 5-bisphosphate (PtdIns(4, 5)P2) and phosphatidylinositol 4-phosphate (PtdIns(4)P). May be involved in spermatogenesis. Interacts with ACTRT3.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PFN3

Profilin-3

PFN3

Molecular Synopsis