FEATURES

FAMILY

DESCRIPTION

Also known as 3SOF5_NAJAT, 3SOF5. Non-cytotoxic protein that does not show lytic and hemolytic activities, but can induce aggregation and fusion of sphingomyelin vesicles (PubMed:8182052). It binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with high affinity, and it inhibits osteoclast differentiation and bone resorption in mice, probably due to binding to integrin alpha-V/beta-3 (PubMed:16407244).

EXTERNAL LINKS

uniprot
enzyme classification

3SOF5

Mutations

Mutation(s) distribution

Mutations table