FEATURES

FAMILY

DESCRIPTION

Also known as ACTG_HUMAN, ACTG1, ACTG. Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Interacts with TWF1, CAPZB, cofilin and profilin (PubMed:28493397).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ACTG1

Actin, cytoplasmic 2

Mutations

Mutation(s) distribution

Mutations table

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