FEATURES

FAMILY

DESCRIPTION

Also known as ASM3A_MOUSE, Smpdl3a, Asml3a. Has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP (PubMed:26792860). Has in vitro activity with p-nitrophenyl-TMP. Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates. Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine. Has in vitro activity with CDP-ethanolamine. Does not have sphingomyelin phosphodiesterase activity (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification

Smpdl3a

Acid sphingomyelinase-like phosphodiesterase 3a

Mutations

Mutation(s) distribution

Mutations table

Search Mutation