FEATURES

FAMILY

DESCRIPTION

Also known as KCNN2_RAT, Kcnn2. Forms a voltage-independent potassium channel activated by intracellular calcium (PubMed:8781233, PubMed:20562108). Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. Heterooligomer. The complex is composed of 4 channel subunits each of which binds to a calmodulin subunit which regulates the channel activity through calcium-binding.

EXTERNAL LINKS

uniprot
enzyme classification

Kcnn2

Small conductance calcium-activated potassium channel protein 2

Mutations

Mutation(s) distribution

Mutations table

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