FEATURES

FAMILY

DESCRIPTION

Also known as AUR24_RANAE, AUR24. Antimicrobial activity against B.cereus, L.lactis, L.innocua, M.luteus, S.aureus, S.epidermidis and S.uberis (PubMed:10951191). Probably acts by disturbing membrane functions with its amphipathic structure (PubMed:10951191). Shows anticancer activity (PubMed:10951191). Strongly inhibits the formation of NO by neuronal nitric oxide synthase (nNOS) at micromolar concentrations (PubMed:11784303). Acts by a non-competitive mechanism, probably by binding to calcium/calmodulin and as a consequence blocking calmodulin attachment to nNOS (By similarity).

Also known as AUR24_RANAE, AUR24. Antimicrobial activity against B.cereus, L.lactis, L.innocua, M.luteus, S.aureus, S.epidermidis and S.uberis (PubMed:10951191). Probably acts by disturbing memb ...

EXTERNAL LINKS

uniprot
enzyme classification

AUR24

Aurein-2.4

AUR24

Structural Ligandability

Domains Chains

Distribution