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FEATURES

FAMILY

DESCRIPTION

Also known as GRFIN_GRISQ, GRFIN. Mixed specificity lectin with anti-HIV activity. Binds to HIV envelope glycoproteins, including exterior membrane glycoprotein gp120, and inhibits viral entry into cells. Binding to gp120 is dependent on gp120 being glycosylated, and is inhibited by mannose, glucose and N-acetylglucosamine.

Also known as GRFIN_GRISQ, GRFIN. Mixed specificity lectin with anti-HIV activity. Binds to HIV envelope glycoproteins, including exterior membrane glycoprotein gp120, and inhibits viral entry into ...

EXTERNAL LINKS

uniprot
enzyme classification

GRFIN

Griffithsin

Molecular Synopsis

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