FEATURES

FAMILY

DESCRIPTION

Also known as RNPH_MYCTU, rph, rphA. Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. Homohexameric ring arranged as a trimer of dimers (Ref.3).

EXTERNAL LINKS

uniprot
enzyme classification

rph

Ribonuclease PH

rph

Molecular Synopsis