FEATURES

FAMILY

DESCRIPTION

Also known as PKNG_MYCTU, pknG. Phosphorylates GarA. May play a role in metabolic regulation via control of the phosphorylation status of GarA. Plays a crucial role in the survival of mycobacteria within host macrophages, by blocking the intracellular degradation of mycobacteria in lysosomes. Required for intrinsic antibiotic resistance. Homodimer. Interacts with the FHA domain of GarA.

EXTERNAL LINKS

uniprot
enzyme classification

pknG

Serine/threonine-protein kinase PknG

pknG

Molecular Synopsis