dut (Deoxyuridine 5'-triphosphate nucleotidohydrolase)

FEATURES

FAMILY

DESCRIPTION

Also known as DUT_LEPBJ, dut. This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION

dut

Deoxyuridine 5'-triphosphate nucleotidohydrolase

LIGANDABILITY MUTATIONS

dut

Molecular Synopsis