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FEATURES

DESCRIPTION

Also known as SOX4_MOUSE, Sox4, Sox-4. Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif (PubMed:8404853). Required for IL17A-producing Vgamma2-positive gamma-delta T-cell maturation and development, via binding to regulator loci of RORC to modulate expression (PubMed:23562159). Interacts with UBE2I.

Also known as SOX4_MOUSE, Sox4, Sox-4. Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif (PubMed:8404853). Required for IL17A-producing Vgamma2 ...

EXTERNAL LINKS

uniprot
enzyme classification

Sox4

Transcription factor SOX-4

Molecular Synopsis

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