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FEATURES

FAMILY

purine/pyrimidine phosphoribosyltransferase family

DESCRIPTION

Also known as HPRT_TRYBB, HGPRT. Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).

Also known as HPRT_TRYBB, HGPRT. Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto ...

EXTERNAL LINKS

uniprot
enzyme classification

HGPRT

Hypoxanthine-guanine phosphoribosyltransferase

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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