FEATURES

FAMILY

CDP-alcohol phosphatidyltransferase class-I family

DESCRIPTION

Also known as CRD1_YEAST, CRD1, CLS1. Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.

EXTERNAL LINKS

uniprot
enzyme classification

CRD1

Cardiolipin synthase (CMP-forming)

CRD1

Structural Ligandability

Domains Chains

Distribution