FEATURES

FAMILY

DESCRIPTION

Also known as ACSA_NITEC, acsA. Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

EXTERNAL LINKS

uniprot
enzyme classification

acsA

Acetyl-coenzyme A synthetase

acsA

Structural Ligandability

Domains Chains

Distribution