FEATURES

FAMILY

DESCRIPTION

Also known as MOC2A_PHANO, cnxG. Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by UBA4. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin. Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.

EXTERNAL LINKS

uniprot
enzyme classification

cnxG

Molybdopterin synthase sulfur carrier subunit

cnxG

Molecular Synopsis