FEATURES

DESCRIPTION

Also known as LIN32_CAEEL, lin-32, hlh-7. Probable transcription factor which binds the E box motif 5'-CA[TC][AG]TG-3' (PubMed:11076762). Essential for the specification of the neuroblast cell fate in the development of peripheral sense organs (PubMed:7800042). Its role in the generation of sensory neurons may be through positively regulating the expression of the zinc finger protein ztf-11 during postdeirid neurogenesis (PubMed:31386623). Required for specification of cell fate, acting in concert with lin-32, in the development of the male-specific genital sensilla (simple sense organs) known as rays (PubMed:11076762). Involved in regulating glial specification, perhaps by suppressing a glial fate in different lineages during early embryogenesis (PubMed:32665354). Forms a heterodimer with hlh-2.

lin-32

Structural Ligandability

Domains Chains

Distribution