FEATURES

DESCRIPTION

Also known as CSN10_YEAST, RRI2, CSN10. Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes. The CSN complex is involved in the regulation of the mating pheromone response. Component of a COP9 signalosome-like (CSN) complex, composed of at least RRI1/CSN5, CSN9, RRI2/CSN10, PCI8/CSN11, CSN12 and CSI1. In the complex, it probably interacts directly with CSN12.

EXTERNAL LINKS

uniprot
enzyme classification

RRI2

COP9 signalosome complex subunit 10

RRI2

Structural Ligandability

Domains Chains

Distribution