FEATURES

DESCRIPTION

Also known as FOXI1_HUMAN, FOXI1, FKHL10, FREAC6. Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

FOXI1

Forkhead box protein I1

FOXI1

Molecular Synopsis