FEATURES

FAMILY

DESCRIPTION

Also known as RAB30_HUMAN, RAB30. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). Required for maintaining the structural integrity of the Golgi apparatus, possibly by mediating interactions with cytoplasmic scaffolding proteins.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RAB30

Ras-related protein Rab-30

RAB30

Molecular Synopsis