FEATURES

FAMILY

DESCRIPTION

Also known as LAT2A_LACTA, LAT2A. It has antimicrobial activity against Gram-positive bacteria (A.globiformis VKM Ac-1112 (MIC=0.7 uM), and B.subtilis VKM B-501 (MIC=0.4 uM)), Gram-negative bacteria (E.coli DH5-alpha (MIC=1.0 uM), E.coli MH1 (MIC=0.7 uM), and P.aeruginosa PAO1 (MIC=6.7 uM)), and yeasts (P.pastoris GS115 (MIC=6.7 uM), and S.cerevisiae Y190 (MIC=54 uM)). Also has a strong hemolytic activity against rabbit erythrocytes. Causes paralysis, but is not lethal when injected into insect (M.domestica) larvae.

EXTERNAL LINKS

uniprot
enzyme classification

LAT2A

M-zodatoxin-Lt2a

LAT2A

Molecular Synopsis