FEATURES

FAMILY

DESCRIPTION

Also known as ACCA_STAA8, accA. Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).

EXTERNAL LINKS

uniprot
enzyme classification

accA

Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha

Mutations

Mutation(s) distribution

Mutations table

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