FEATURES

DESCRIPTION

Also known as SBNI_STAA8, sbnI. Free serine kinase that uses ATP to phosphorylate L-serine to yield O-phospho-L-serine and ADP. O-phospho-L-serine serves as a substrate for SbnA and is a precursor for staphyloferrin B biosynthesis (PubMed:29483190). Is also a DNA-binding regulatory protein that senses heme to control gene expression for siderophore biosynthesis. Binds to DNA within the sbnC coding region and is required for expression of genes in the sbn operon from sbnD onward (PubMed:26534960). Forms dimers and tetramers in solution (PubMed:26534960). Predominantly forms dimers (PubMed:29483190). Dimerization/oligomerization is not essential for kinase activity (PubMed:29483190).

EXTERNAL LINKS

uniprot
enzyme classification

sbnI

L-serine kinase SbnI

sbnI

Molecular Synopsis