FEATURES

FAMILY

DESCRIPTION

Also known as DPOL_BPR69, 43. Replicates the viral genomic DNA. This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction for proofreading purpose. Part of the replicase complex that includes the DNA polymerase, the polymerase clamp, the clamp loader complex, the single-stranded DNA binding protein, and the primase/helicase (By similarity). Interacts with the polymerase clamp; this interaction constitutes the polymerase holoenzyme (PubMed:10535734).

EXTERNAL LINKS

uniprot
enzyme classification

43

Mutations

Mutation(s) distribution

Mutations table