FEATURES

FAMILY

DESCRIPTION

Also known as SKAP2_MOUSE, Skap2, Prap, Ra70, Saps, Scap2, Skap55r. May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway. Interacts with LAT, GRB2, PTK2B and PRAM1 (By similarity). Homodimer. Interacts with FYB1, which is required for SKAP2 protein stability. Interacts with PTPNS1. Part of a complex consisting of SKAP2, FYB1 and PTPNS1. Part of a complex consisting of SKAP2, FYB1 and LILRB3. May interact with actin. May interact with FYN, HCK and LYN. Interacts with FASLG (By similarity).

Also known as SKAP2_MOUSE, Skap2, Prap, Ra70, Saps, Scap2, Skap55r. May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to int ...

EXTERNAL LINKS

uniprot
enzyme classification

Skap2

Src kinase-associated phosphoprotein 2

Skap2

Molecular Synopsis