FEATURES

FAMILY

DESCRIPTION

Also known as TERT_TAKRU, tert. Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalytic subunit of the telomerase holoenzyme complex composed minimally of TERT and the telomerase RNA template component (TERC).

EXTERNAL LINKS

uniprot
enzyme classification

tert

Telomerase reverse transcriptase

Mutations

Mutation(s) distribution

Mutations table

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