FEATURES

FAMILY

CRISPR-associated endonuclease Cas1 family

DESCRIPTION

Also known as CAS1C_THET8, cas1-3. CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. Homodimer, forms a heterotetramer with a Cas2 homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

cas1-3

CRISPR-associated endonuclease Cas1 3

cas1-3

Structural Ligandability

Domains Chains

Distribution