FEATURES

DESCRIPTION

Also known as GRAR_STAAC, graR. Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs) (By similarity) (PubMed:17502406). Upon phosphorylation by GraS, functions as a transcription regulator by direct binding to promoter regions of target genes such as adhesins, exoproteins, transporters, toxins, and proteins involved in cell wall synthesis. Down-regulates the expression of many genes involved in RNA and amino acid synthesis or glycolysis (By similarity). Interacts with GraX.

EXTERNAL LINKS

uniprot
enzyme classification

graR

Response regulator protein GraR

graR

Molecular Synopsis