FEATURES

FAMILY

DESCRIPTION

Also known as TMBL2_THEKO, trmBL2. An abundant chromosomal protein that seems to be involved in both genome architecture and transcription repression. Incubation with DNA in vitro gives fibrous structures 14.2 +/- 2.1 nm in thickness (naked DNA is 1.83 +/- 0.37 nm); does not significantly compact DNA. Binds to both coding and non-coding regions; binding within gene promoters correlates with decreased transcript levels, while binding within coding regions does not.

EXTERNAL LINKS

uniprot
enzyme classification

trmBL2

HTH-type transcriptional regulator TrmBL2

trmBL2

Molecular Synopsis