FEATURES

FAMILY

DESCRIPTION

Also known as R15PI_THEKO, TK0185. Catalyzes the isomerization of ribose 1, 5-bisphosphate (R15P) to ribulose 1, 5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Only accepts the alpha-anomer of D-ribose 1, 5-bisphosphate as substrate, being inactive on the beta-anomer. Displays a strict substrate specificity, since other phosphorylated sugars such as R5P, ribose, G16P, G6P, G1P, FBP, F6P, and PRPP, are not substrates. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO. Homohexamer; trimer of dimers.

EXTERNAL LINKS

uniprot
enzyme classification

TK0185

Mutations

Mutation(s) distribution

Mutations table