FEATURES

DESCRIPTION

Also known as FAIM3_RAT, Fcmr, Faim3, Toso. May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification

Fcmr

Fas apoptotic inhibitory molecule 3

Fcmr

Structural Ligandability

Domains Chains

Distribution