FEATURES

FAMILY

DESCRIPTION

Also known as APCA_AROAE, apc1, apcA. Catalyzes the carboxylation of acetophenone to form 3-oxo-3-phenylpropanoate (benzoylacetate) in the anaerobic catabolism of ethylbenzene. Also carboxylates propiophenone at the same rate and 4-acetyl-pyridine at lower rates. Acetophenone carboxylase consists of five subunits; a heterooctameric subcomplex of two alpha (Apc1), two beta (Apc2), two gamma (Apc3) and two delta (Apc4) subunits assembles with the epsilon (Apc5) subunit in an unknown stoichiometry.

EXTERNAL LINKS

uniprot
enzyme classification

apc1

Acetophenone carboxylase alpha subunit

Mutations

Mutation(s) distribution

Mutations table

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