FEATURES

FAMILY

DESCRIPTION

Also known as CWC15_PONAB, CWC15. Involved in pre-mRNA splicing as component of the spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Identified in the spliceosome C complex. Component of the PRP19-CDC5L splicing complex composed of a core complex comprising a homotetramer of PRPF19, CDC5L, PLRG1 and BCAS2, and at least three less stably associated proteins CTNNBL1, CWC15 and HSPA8. Interacts directly with CTNNBL1 in the complex.

EXTERNAL LINKS

uniprot
enzyme classification

CWC15

Spliceosome-associated protein CWC15 homolog

CWC15

Molecular Synopsis