FEATURES

FAMILY

class-II aminoacyl-tRNA synthetase family

DESCRIPTION

Also known as SYD_THET8, aspS1. Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp). Is specific for tRNA(Asp) since it aspartylates tRNA(Asn) 3 orders of magnitude less efficiently than tRNA(Asp). Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

aspS1

Aspartate--tRNA(Asp) ligase

Mutations

Mutation(s) distribution

Mutations table

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