FEATURES

FAMILY

DESCRIPTION

Also known as RRAAH_BACCZ, BCE33L3012. Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity). Homotrimer.

EXTERNAL LINKS

uniprot
enzyme classification

BCE33L3012

Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase

BCE33L3012

Molecular Synopsis