FEATURES

FAMILY

DESCRIPTION

Also known as TAF2_HUMAN, TAF2, CIF150, TAF2B. Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. It requires core promoter-specific cofactors for productive transcription stimulation. TAF2 stabilizes TFIID binding to core promoter. Component of transcription factor TFIID which is composed of TBP and a number of TBP-associated factors. Interacts with TAF2C1. Component of the TFTC-HAT complex.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TAF2

Mutations

Mutation(s) distribution

Mutations table