FEATURES

DESCRIPTION

Also known as EPA2B_XENLA, Pabpn1l-b, epabp2-b, pabpnl1-b. Binds the poly(A) tail of mRNA. Unable to interact with the cap-binding complex and is therefore unlikely to be involved in translation initiation. Homodimer; Upon poly(A) binding, undergoes a dimer-monomer transition that removes the polyproline motif from the RNA recognition site and allows it to be replaced by the adenosine nucleotides of poly(A).

EXTERNAL LINKS

uniprot
enzyme classification

Pabpn1l-b

Embryonic polyadenylate-binding protein 2-B

Mutations

Mutation(s) distribution

Mutations table

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