FEATURES

FAMILY

CRISPR-associated endoribonuclease Cas2 protein family

DESCRIPTION

Also known as CAS2A_SYNY3, cas2-1. CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. Homodimer, forms a heterotetramer with a Cas1 homodimer.

EXTERNAL LINKS

cas2-1

Mutations

Mutation(s) distribution

Mutations table