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Also known as KCTD8_HUMAN, KCTD8. Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity). Interacts as a tetramer with GABRB1 and GABRB2.

Also known as KCTD8_HUMAN, KCTD8. Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-prote ...

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uniprot
enzyme classification
PhosphoSitePlus

KCTD8

BTB/POZ domain-containing protein KCTD8

Mutations

Mutation(s) distribution

Mutations table

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