FEATURES

DESCRIPTION

Also known as 5S_PROFR, 5S. The 5S subunit specifically catalyzes the transfer of the carboxyl group from biotin of the 1.3S subunit to pyruvate to form oxaloacetate and 1.3S biotin. Homodimer. Transcarboxylase is composed of three subunits: 1.3S, 5S, and 12S. The core of the enzyme is composed of six 12S subunits. On each side of the core there are three pairs of 5S subunits. Each 5S dimer is attached to the core by two 1.3S subunits. Thus the total number of chains is 30 (6 + 12 + 12).

EXTERNAL LINKS

uniprot
enzyme classification

5S

Methylmalonyl-CoA carboxyltransferase 5S subunit

Mutations

Mutation(s) distribution

Mutations table

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